Spice
Black Pepper
6/10 Moderate evidence
Common kitchen spice whose alkaloid piperine dramatically enhances absorption of curcumin and other polyphenols.
Active compounds
-
Piperine
Inhibits glucuronidation in the liver, increasing systemic availability of other compounds
Helps with
Practical tips
- Preparation
- Use freshly cracked; pre-ground loses volatile oils quickly
- Recommended amount
- 1/4 teaspoon with turmeric-containing meals
- Absorption
- Even a small pinch with curcumin boosts curcumin absorption by up to 2000%
- Cautions
- Piperine alters drug metabolism — may affect levels of medications cleared by glucuronidation